Analytical Technologies

Analytical Technologies

The qualitative approach can be used to analyze the composition of substances which are natural or synthetic and then determine whether the compound is used in the pharmaceutical development. Additionally, qualitative analysis is also widely used in the detection of physicochemical properties, such as the flavor, precipitates, color changes, and melting/boiling point, to evaluate the product’s quality. The quantitative analytical techniques is a method used to quantitatively analyze the content of a compound or substances in a material. Many techniques can be used as quantitative analytical techniques including the mass spectrometry, chromatographic techniques, electrophoretic methods and other approaches for characterization of biotechnology products such as capillary electrophoresis, hyphenated techniques, and spectroscopy.

Our Analytical Technologies

  • Chromatography: UPLC, HPLC, LC-MS, GC, GC-MS, IC, SFC
  • Solid state characterization: XRPD, DVS, DSC, TGA with MS interface, PSD, nano-particle size analyzer, polarized light microscope, SEM, surface area analyzer
  • Capillary electrophoresis (CZE, CE-IEF, CE-SDS; UV and LIF detection)
  • Electrophoresis (IEF, SDS-PAGE, native gel; standardized and ready gels)
  • Mass spectrometry (ESI, MALDI-TOF/TOF-MS)
  • Identification: NMR, FT-IR
  • Quantitative PCR, threshold system
  • Light scattering (MALS, DLS)
  • General testing: KF, UV-Vis, Polarimeter
  • Elemental analyzer: ICP-OES, ICP-MS
  • USP dissolution apparatus type I and II
  • Stability & photostability chambers
  • Western blotting
  • Analytical ultracentrifugation
  • DNA sequencing (cGMP)

Why Choose BOC Sciences?

BOC Sciences has a great bio/pharmaceutical analysis capability to meet requirements for isolation, identification and characterization of a broad range of chemical compounds and large molecules. Our series of top-notch instrumentations enable our scientists to offer you a full range analysis report so as to support your drug development program. Although the majority of biotechnology products are composed of homogeneous types or mixture of large and complex molecules, our experts are able to help you determine the detailed composition of the products in a timely and accurate manner. We provide full range characterization studies including method development, validation, and transfer, as well as the quality control and batch release analysis.

References

  1. Lindon, J. C., & Nicholson, J. K. (2008). Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery. TrAC Trends in Analytical Chemistry27(3), 194-204.
  2. Munir, M. T., Yu, W., Young, B. R., Wilson, D. I., Information, I., & Centre, C. (2015). The current status of process analytical technologies in the dairy industry. Trends in Food Science & Technology, 43(2), 205-218.

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