Custom Synthesis
BOC Sciences offers custom synthesis and manufacturing services for biotechnology, pharmaceutical, life science, chemical research and related industries. A series of chemical reactions are carried out for the purpose of obtaining one or more organic molecules. As an integral part of drug discovery or other chemical industries, chemical synthesis plays an important role in the screening of numerous potential active ingredients.
Our custom chemical synthesis services:
Active pharmaceutical ingredient (API) is a part of drug product that produces primary therapeutic effects. Some kinds of dosage forms, such as compound preparation, possess two or more active ingredients that is designed to treat different symptoms or integrate synthetical effects.
Chiral synthesis, also known as enantioselective synthesis, has a great importance in the screening of APIs and development of bio/pharmaceutical products.
Bioconjugation represents the technique of giving a target substance with certain desired properties through the site-specific reaction between the biomolecules and exogenous moieties (usually one or several other molecules). Through such covalent linkage approach, a broad range of innovative drug substances or end products are designed to improve the accuracy of disease diagnosis, pharmacokinetic properties, treatment efficacy and many other aspects.
An effective process R&D is an essential part of your drug development while it plays important role in controlling costs, ensuring product’s quality and meeting the requirements of regulations. More importantly, package solutions are available to address any problems and potential risks that significantly impact the quality of your products.
Chemical reactions are the processes by which chemicals interact to form new chemicals with different compositions. Simply stated, a chemical reaction is the process where reactants are transformed into products. How chemicals react is dictated by the chemical properties of the element or compound-the ways in which a compound or element undergoes changes in composition.
Polycyclic Aromatic Hydrocarbons Synthesis
Nucleosides & Nucleotides Synthesis
Carbohydrate Synthesis
Peptide Synthesis
Steroids Synthesis
Flavors-fragrance Synthesis
Semi-synthesis and Total Synthesis of Natural Products
The practice of stable isotope labeling is a widely utilized method across the scientific disciplines, spanning chemistry, biology, and environmental science, among others, in order to effectively monitor the migration of atoms or molecules within a given system. The process itself involves the substitution of one or more atoms present within a molecule with a stable isotope of the identical element, wherein the likes of carbon-12 is supplanted by carbon-13, for example.
Why BOC Sciences?
- Synthetic Route Design and Optimization
- Process Research, Development, and Optimization
- Small- and Large-Scale Chemistry Capabilities
- Advanced Synthetic and Analytical Platform
- Expert Project Management
- Cost-Effectiveness and High Efficiency
Common chemical reaction type
| Michael addition | Friedel-Crafts reaction |
| Stille Coupling | High-pressure hydrogenation |
| Suzuki Coupling | Asymmetric hydrogenation |
| Chiral Synthesis | Heterocyclic formation |
| Fluorination | Oxidation/Reduction |
Custom synthesis chemical documents are available:
Synthesis procedure (original synthesis records, TLC, etc), high performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), nuclear magnetic resonance analyses (NMR), etc.
Custom process
References
- Piletsky, S., Piletska, E., Karim, K., Foster, G., Legge, C., & Turner, A. (2004). Custom synthesis of molecular imprinted polymers for biotechnological application: Preparation of a polymer selective for tylosin. Analytica chimica acta, 504(1), 123-130.
- Blackburn, G. M., Cherfils, J., & Moss, G. P. (2018). A critical review of the proposed definitions of fundamental chemical quantities and their impact on chemical communities (IUPAC Technical Report). Chemistry International.
- Tyson, R. (1988). Custom synthesis and process development. Chemistry and Industry, 118-22.