One of the main problems associated with poorly soluble drugs is the low bioavailability and poor solubility. Formulation as a nanosuspension is an attractive and promising alternative to address these issues. Nanosuspensions consist of poorly soluble drugs that are insoluble in water and oil, and the solid particles have a particle size distribution typically less than 1 micron, which enhances the solubility of poorly water soluble drugs as well as lipid media. Nanosuspensions are simple to prepare and have been developed as promising candidates for the effective delivery of hydrophobic drugs, typically for oral and topical use or parenteral and pulmonary administration. The nanosuspension not only solves the problem of poor solubility and bioavailability, but also changes the pharmacokinetics of the drug, thereby improving the safety and effectiveness of the drug.
BOC Sciences is developing a range of formulations using nanosuspension technology, including drug delivery systems, controlled release systems and more. These products present multiple challenges to product characterization. However, we have experienced analysts and nanoparticle engineering professionals who have comprehensive R&D or Good Manufacturing Practice (cGMP) analytical capabilities for nano-sized particle or suspension systems. In addition, we offer comprehensive expertise with quality guaranteed to help you meet and exceed quality, safety and regulatory standards.
BOC Sciences develops nanosuspension and microemulsion formulations that enhance drug solubility and stability for improved therapeutic performance.
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